Department of Physics

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    Synthesis and Characterization of Silver Nanoparticles as Cholesterol Biosensor
    (Library Information Services, COMSATS University Islamabad, Lahore Campus, 2019) Fawad Masood; CIIT/FA17-RPH-017/LHR; Dr. Akbar Ali; LHR TP 5717
    In the present research work, the AgNPs are synthesized by the chemical reduction method by using AgNO3 as a reducing agent and NaBH4 as stabilizing agent and reducing agent as well. The structural properties are investigated by X-ray diffraction (XRD) spectroscopy. XRD reveals the cubic structure and calculate the Crystallite size of the prepared sample. Fourier transform infrared spectroscopy (FTIR) is used to investigate the chemical bond vibrations of the different groups present in AgNPs. UV- Vis spectroscopy is carried out to observe the abortion spectrum of AgNPs. In case of UV-Vis, the absorption spectra show a sharp fall in absorbance spectrum near the band edge indicating that the material has a direct bandgap. The surface morphology is investigated by the scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Afterwards, synthesized AgNPs are used for the fabrication of cholesterol biosensor. For the fabrication of biosensor, we have used three electrode system. We have used glassy carbon electrode (GCE) as working electrode. Finally the electrochemical measurements have performed for the different concentration of cholesterol. We have obtained the linearity between the potential difference and concentration of cholesterol, which shows that our material is effective for the fabrication of cholesterol biosensor.
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    Study of Magnetic Iron Oxide Nanoparticles and their Application as a Glucose Biosensor
    (Library Information Services, COMSATS University Islamabad, Lahore Campus, 2019) IBRAR AHMED; CIIT/FA17-RPH-035/LHR; Dr. Akbar Ali; LHR TP 5725
    Fe3O4 nanoparticles have been used as a drug delivery in medical, biosensing and bioimaging. Due to quick response time it is used for biosensing. In this study, Fe3O4 nanoparticles were prepared by Coprecipitation method with variation in stirring time. The prepared material was characterized by XRD, SEM and FTIR. Single phase composite material examined by XRD and average crystallite size found to be 60nm. SEM images shows the proposed material is homogeneous and dense. The working electrode was prepared successfully using glassy carbon. The electrochemical measurement is performed for different concentration of glucose. Increment in glucose concentration gives the linear response in form of higher potential.