Fabrication and Characterization of Polymeric Aminopropyltriethoxysilane Silica-based Hemodialysis Membrane

Abstract

Kidneys are an important part of human body. The function of kidneys is to remove toxic effluent and fluids from the blood and sustain the specific quantity of liquid in body to operate properly. When human kidney fail to work up to 90% either due to some disease or other reason, then patient body become loaded with toxic surplus. This can lead to kidney failure and even life intimidating if left untreated. There are some methods for the treatments of kidney failure in which the important one is hemodialysis therapy. In hemodialysis, human blood is passed through a hemodialysis machine, where most important component of the entire set up is semipermeable dialysis membrane, which has a tremendous impact on the quality and quantity to remove the unwanted uremic toxins from the blood of the patient who have been dealing with the kidney failure. Suitability of the hemodialysis membrane based on biocompatibility factor that depend on membrane chemical composition. Lower risk of death suffered to the patient when dialyzed with membranes that are highly biocompatible. Thus, current work is focused to develop a hemodialysis membrane based on novel formulations and methodology that is highly biocompatible when treated with real human body and also successfully removes the uremic toxins from the model solution of uremic toxins.