Synthesis and Characterization of Imine Linked-Covalent Organic Frameworks for Drug Control Release Studies

Abstract

Covalent organic frameworks (COFs) are new class of emerging porous crystalline materials that have outstanding properties like high surface area, less density and controlled pore size and structure. Owing these outstanding properties COFs proved themselves as excellent materials in numerous fields such as gas separation, gas storage, energy storage, catalysis and biomedical. Based on different building units COFs have been classified into boron containing COFs, imine-based COFs, hydrazine-based COFs and imide-based COFs. Various synthetic approaches have been explored for the construction of COFs such as solvothermal method, microwave method, ionothermal method and room temperature synthesis method. Two factors are very important for the synthesis of COFs, one is selection of building units and second is suitable conditions. Here we synthesize imine linked COF at room temperature. Successful synthesis of imine linked COF-LZU1 was done by the condensation reaction between Triformyl benzene and 1,4-diaminobenzene. COF-LZU1 was modified with Ag particles by the reaction between silver nitrate and COF-LZU1. Synthesis of COF-LZU1 and Ag@COF-LZU1 was confirmed by FTIR and XRD. In FTIR spectra C=N appears at 1616 cm-1 that confirms the condensation reaction between two selected monomers. In XRD strong diffraction peak at 2Ɵ at 4.78o confirms the crystalline nature of COF-LZU1. COF-LZU1 showed the photocatalytic degradation of MB and CR dyes in visible light with percentage degradation of 72.21 and 67.7, respectively.