Department of Chemistry
Permanent URI for this communityhttps://repository.cuilahore.edu.pk/handle/123456789/14
Browse
3 results
Search Results
Item Development of a Modified Porphyrin Based Composite for Biomedical Application(Library Information Services, COMSATS University Islamabad, Lahore Campus, 2025) Husnain Ali Awan; CIIT/SP24-R06-022/LHR; Dr. M. Shahid Nazir; LHR TP 10026Zn-TCPP@CNC, a novel fluorescent nanocomposite was prepared by conjugation of Zn-TCPP and CNC. That Zn2+ ions have been successfully coordinated with the porphyrin core, the key functional groups are retained, and the MOF interacts well with the CNC support have been confirmed by structural and optical characterizations, such as UV-Vis, FTIR, and XRD. FESEM analysis showed rod shaped morphology with MOF particles decorated on the surface, this leads to high surface area and less aggregation of the MOF particles, which is ideal in sensing application. Fluorescence of Zn-TCPP@CNC was studied in the process of selectively detecting ascorbic acid. The material had maximum absorption at 420 nm, and showed fluorescence emission spectra with peaks between 600-700nm, which was effectively quenched with the help of ascorbic acid through a photoinduced electron transfer process. Optimization experiments have shown that a material concentration of 200 mL gave both stable and reproducible fluorescence values. The specificity of the sensor was proved by selectivity experiments, which showed low interference with glucose, fructose, urea, uric acid and biogenic amines. Sensitivity analyses demonstrated that the quenching effect was concentration-dependent, and, therefore, allowed the quantitative determination of ascorbic acid. The slope of the calibration curve and the standard deviation of the blank values were used to determine the limit of detection (LOD) which is 18.29 µM. This is explained by the fact that quenching is because of effective molecular interactions, such as hydrogen bonding and photoinduced electron transfer. These findings suggest that Zn-TCPP@CNC is a sensitive, selective, and reliable platform of fluorescence detection of ascorbic acid.Item Cellulose Nanozyme Composites for the Remediation of Pharmaceutical Wastewater(Library Information Services, COMSATS University Islamabad, Lahore Campus, 2025) Wasama Intikhab; CIIT/SP24-R06-020/LHR; Dr. M. Shahid Nazir; LHR TP 10025In this research, the synthesis and description of a cellulose nanocrystal (CNC) derived Zn0.5Mn0.5Fe₃O₄ composite will be sought in which the intended purpose will be to utilize the compound in the treatment of pharmaceutical wastewater. The rationale behind the use of the CNC is that it is biocompatible with high surface area and has the potential to provide a successful support structure of metal oxides. The compounds were found to be very effective in removing contaminants, which was enhanced by the addition of Fe3O4, Zn and Mn nanoparticles that enhanced the catalytic and adsorption characteristics of the compounds. It was determined, as a consequence of the experimental work, that the Zn0.5Mn0.5Fe₃O₄@CNC composite exhibited a good catalytic degradation of pharmaceutical contaminants and most particularly under varied pH condition and greatest activity at pH alkalinity. The effectiveness of the functionalization and stability of the composite structure in the degradation process was validated by the UV-vis analysis and FTIR analysis. The paper introduces the prospect of the Zn0.5Mn0.5Fe₃O₄@CNC composite as a new environmental friendly and a high promising material in the process of advanced wastewater treatment that will serve as a sustainable solution to the pharmaceutical pollution and will aid in preserving the environment and human health.Item Facile Synthesis of MOF for Enhanced Photo- fenton Degradation of Pesticide from Model Wastewater(Library Information Services, COMSATS University Islamabad, Lahore Campus, 2025) Amir Mushtaq; CIIT/SP24-R06-001/LHR; Dr. M. Shahid Nazir; LHR TP 10013Metal organic frameworks (MOFs) have proved to be a porous material of high surface area, adjustable chemical properties, whereas spinel ferrite nanoparticles have distinct magnetic and electronic properties and their composites are of great interest to the environment. In this research, a useful and efficient photocatalytic compound, MOF-5 and Zn0.5Mn0.5Fe2O4, was effectively prepared by attaching the Zn0.5Mn0.5Fe2O4 nanoparticles onto the MOF-5 structure. X-ray Diffraction (XRD) analysis revealed the existence of typical diffraction peaks of the two MOF-5 and Zn0.5Mn0.5Fe2O4, which show that the composite was formed without phase segregating and the crystalline structure of MOF-5 remained intact. Fourier Transform Infrared Spectroscopy (FTIR) showed several peaks of the metal-oxygen and metal-metal-oxygen stretching vibrations of Zn0.5Mn0.5Fe2O4 and the vibrations of the MOF-5 organic linkers indicating that the nanoparticles were highly interacting with the MOF framework. The distribution of Zn0.5Mn0.5Fe2O4 nanoparticles in porous MOF-5 was shown based on the Scanning Electronic Microscopy (SEM) images, which indicated a uniform distribution in the interconnected microstructure of the material, resulting in high surface area and easy accessibility of the active site. The composite was studied by UV- Visible spectroscopy, revealing specific absorption peaks within the range of 200-800 nm, with minor variations to pure MOF-5, and bandgap was calculated to be 1.87 eV, which has better light-harvesting properties and the possibility of visible-light driven photocatalysis. Under optimal conditions identified with the analysis of the Design Expert, the degradation of imidacloprid in model wastewater was performed under following conditions: reaction pH 4, a constant dosage of 10 mg catalyst, 112.5 μL hydrogen peroxide, and 40 ppm imidacloprid in 10 min reaction time, and the maximum degradation efficiency reached 97.95%, this highlights composite’s efficiency and applicability in environmental remediation.