M.Phil / MS

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This collection archives the complete set of theses produced by students of the COMSATS University Islamabad, Lahore Campus.

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    Fabrication Of Body Equivalent Tissue Phantom For The Evaluation Of Breast Cancer By Radiation Therapy
    (Library Information Services, COMSATS University Islamabad, Lahore Campus, 2021) ABDUL MUGHNI; CUI/FA18-RPH-048/LHR; LHR TP 7245; Dr. Naima Amin
    Preparing a phantom is a highly specialized testing object utilized in medical physics for dosimetry and evaluation of the effect of the dose distribution on cancer cells. The phantom is the best cancer investigational tool for the Medical Physicist. We will be preparing these phantoms to use as our training model. The phantom will be prepared like a real part of the human body tissues. The body or particular organ tissue-equivalent phantom was designed to minimize uncertainties in dosage measurements and treatment plan and also find the track followed by the high energy photon beam. After the preparation of our phantom, we investigate the center and surface doses by the radio-chromic film, it will be helpful in future research. The gel phantom will be irritated with the help of a photon beam and an electron beam of different energies. In this research, we will explore the diffusion of radiation in the irradiated part of the phantom and its effect on normal healthy cells of the phantom. These radiations aim to destroy a cancer cell's DNA. These radiation treatments usually include risks for adjacent healthy tissues within a f ew millimeters. Estimating ionizing radiation is important before cancer therapy. Breast cancer is reinduced by inappropriate radiation usage. Estimation of the radiation dosage may be made more precise for future treatment of any malignancy when the patient is repeatedly irradiated. The main difficulty in radiation treatment is providing a specified dosage to normal tissues. A severe lesion in healthy tissues may impede genome replication and transcription an d, if not corrected, lead to mutations that endanger the survival of cells or organs. Another aspect of this project is to revise the estimation and study of the dose calculation for further cancer treatment to keep safe the human body cells
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