Browsing by Author "Ayesha Khalid"

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Development of Antibacterial & Osteogenic Nanocomposite Membranes for Guided Bone Regeneration
(Library Information Services COMSATS University Islamabad Lahore Campus, 2020-02-25) Ayesha Khalid; FA19-R06-012; Dr. Aqif Anwar Chaudhry; LHR TP 7345
A number of treatments and modalities have been reported to fasten the process of bone regeneration including guided bone regeneration where a barrier membrane provides an isolated space and medium to the defect site to recover quickly without the intervention of surrounding soft tissues. Despite several advantages of both resorbable and non-resorbable membranes, resorbable membranes are usually preferred as they don’t need a second surgery for their removal. They also degrade easily whilst performing the required function of bone restoration. For clinical applications, gelatin/chitosan blend have warrant attention as they provide unique properties. Gelatin possesses RGD like sequences which facilitate cell attachment and migration whereas chitosan is another bioactive and degradable polymer that is widely used in many applications. High degradability, however, may lead to loss of mechanical strength. To overcome this problem, certain cross-linkers are added with the intention of increasing strength and extending the time of degradation.
Role of Creative Discourse on Organizational Politics & Organizational Learning
(Library Information Services COMSATS University Islamaabad Lahore Campus, 2018) Ayesha Khalid; FA16-RMS-002; Kashif Luqman; LHR TP 5677
The aim of this study is to explore the role of creative discourse spaces in organizational politics and organizational learning. Literature on politics and organizational learning brings to the fore two imperative roles of politics in organizational learning. On the one hand, the traditional literature on the links between organizational politics and organizational learning portrays politics as destructive effects on organizational learning. On the other hand, a few studies have posited organizational politics as a source of enhancing organizational learning. The literature also suggests that in the presence of spaces for creative discourse in organization, employees involve in organizational politics that enhances organizational learning; while the unavailability of discourse can result in politics that is harmful for organizational learning. However, despite invaluable contributions in the literature and practice, the theoretical underpinning and empirical literature on the role of creative in organizational politics and organizational learning is non-existing. By using qualitative case studies of two companies as a research methodology, this study aims to explore the role of creative discourse spaces in shaping organizational politics which is constructive for organizational learning. The key reason to use this methodology is the lack of theory on the links between creative discourse, organizational politics (both constructive and destructive) and organizational learning. As a contribution in theory, the present study will contribute how spaces for creative discourse can affect organizational politics and learning. The study will suggest that organizational politics should not be considered essentially negative for organizational learning. Instead, the managers need to provide employees with spaces for free and open dialogue and discussion and focus on offering them opportunities for experimentation. This would create politics in the form of tensions and contestations and the exploitation of these contestations in ways that are constructive for organizational learning.
Role of Creative Discourse on Organizational Politics & Organizational Learning
(Library Information Services, COMSATS University Islamabad, Lahore Campus, 2019) Ayesha Khalid; FA16-RMS-002; Dr. Hafiz Muhammad Usman; LHR TP 5438
The aim of this study is to explore the role of creative discourse spaces in organizational politics and organizational learning. Literature on politics and organizational learning brings to the fore two imperative roles of politics in organizational learning. On the one hand, the traditional literature on the links between organizational politics and organizational learning portrays politics as destructive effects on organizational learning. On the other hand, a few studies have posited organizational politics as a source of enhancing organizational learning. The literature also suggests that in the presence of spaces for creative discourse in organization, employees involve in organizational politics that enhances organizational learning; while the unavailability of discourse can result in politics that is harmful for organizational learning. However, despite invaluable contributions in the literature and practice, the theoretical underpinning and empirical literature on the role of creative in organizational politics and organizational learning is non-existing. By using qualitative case studies of two companies as a research methodology, this study aims to explore the role of creative discourse spaces in shaping organizational politics which is constructive for organizational learning. The key reason to use this methodology is the lack of theory on the links between creative discourse, organizational politics (both constructive and destructive) and organizational learning. As a contribution in theory, the present study will contribute how spaces for creative discourse can affect organizational politics and learning. The study will suggest that organizational politics should not be considered essentially negative for organizational learning. Instead, the managers need to provide employees with spaces for free and open dialogue and discussion and focus on offering them opportunities for experimentation. This would create politics in the form of tensions and contestations and the exploitation of these contestations in ways that are constructive for organizational learning.
Synthesis and Yield Optimization of Polyhydroxyalkanoates (PHA) from Sugarcane Molasses using the Bacterium Priestia Megaterium DSM 3228
(Library Information Services, COMSATS University Islamabad, Lahore Campus, 2025) Ayesha Khalid; SP23-R06-008; Prof. Dr. Robina Farooq; LHR TP 9468
The polyhydroxyalkanoates (PHA) act as intracellular energy storage substances in many prokaryotes. These bio-based polymers biodegradable and biocompatible. Short and medium chain length PHAs are industry produced by m icroorganisms and their enzymes . Short-chain length PHA is produced by the well-known bacterium Priestia megaterium (previously Bacillus megaterium). The goal of the study is to optimize PHA yield and improve the efficiency of the manufacturing process by examining different concentrations of carbon and nitrogen compounds . At a pH of 7 and temperature 37°C, the culture medium supplemented with 17 g/L sugarcane molasses as the carbon source and 0.05 g/L ammonium sulphate as the nitrogen source produced a maximum PHB of 0.95 g/L. The investigation has shown that FTIR can be used as an indirect method for determining the presence of PHB. The FTIR analysis confirmed the biopolymer's structure as polyhydroxybutyrate (PHB) by detecting the presence of methyl, methylene, hydroxyl, and ester carbonyl groups. Polyhydroxyalkanoates (PHA) and their monomeric components were identified using GC-MS chromatography.