Abstract:
Tetracycline works well against both gram-positive and gram-negative bacteria, hence
considered an important antibiotic that is frequently used to treat bacterial illnesses
and respiratory issues in both people and animals. Sometimes, when it is negligibly
overdosed on some animals, its residues accumulate in that animal's body and become
a part of its milk, which is considered unfit for drinking purposes because these
residues cause various health problems such as liver damage, chromosomal
abnormalities, and decreased level of carotenoid. That’s why continuous milk
monitoring is necessary to avoid the health risks caused by these antibiotic residues.
For this purpose, in this research lab made POM based electrochemical sensor was
fabricated for the determination of tetracycline residues in milk. A conductive
filament was synthesized by incorporating POM and graphite in PLA, which was
directly used as a working electrode without any further modification. FTIR was used
for the characterization of this electrode, micro-CT and FE-SEM were also utilized to
explore the internal and surface morphology. Iron substituted wells-dawson POM was
characterized by utilizing FTIR, XRD, and UV-visible spectroscopy. Tetracycline was
successfully detected by this working electrode with a linear range of 4 µM to 500
µM and a LOD of 0.09 µM.