Abstract:
This research requires synthesizing of rGO/Fe3O4/CS nanobiocomposite to fabricate
Screen Printed Electrodes (SPEs), which will be used to detect norepinephrine (NE).
They are Fe3O4 nanoparticles that are of magnetic nature, chitosan which are
biocompatible and rGO which has appreciable electrical conductivity were combined in
an efficient and environmentally friendly manner by co-precipitation method to produce
the nanobiocomposite. Characterization of rGO/Fe3O4/CS was done using FTIR, SEM,
XRD, Raman, and UV-Vis spectroscopy through which the structure and morphology of
the synthesized material were explained. Experiments done using EIS and cyclic
voltammetry indicate that the modified SPEs were electrochemically more sensitive to
NE analyze than the bare SPEs. Thus, application of the rGO/Fe3O4 and CS electrodes
led to the decrease in the effective limit, increasing the sensitivity and expanding the
linear range of detection. The utilization of the nanocomposite components might be
because of the synergistic impact in regard to electron transfer rates and a high NE
adsorption surface. This work bearing futuristic facts in neurochemical surveillance and
medical diagnosing establishes the possibility of employing SPEs incubated with
rGO/Fe3O4/CS nanobiocomposite as a reliable and effective system for neurotransmitter
detection.
