Abstract:
This study focuses on the fabrication and characterization of a Co3O4-Fe2O3-Chitosan
ternary nanobiocomposite electrode for detecting neurotransmitters, with a specific
emphasis on Norepinephrine. The combination of these materials creates a unique
electrochemical platform that offers enhanced sensitivity and selectivity for the detection
of neurotransmitters, which are crucial biomarkers in diagnosing neurological diseases.
The research involved synthesizing and analyzing Co3O4 nanoparticles, Co3O4-Fe2O3 (3:1)
nanocomposites, Co3O4-Fe2O3-CS (3:1:2%) nanobiocomposites, and Co3O4-Fe2O3-CS
(3:1:1%) nanobiocomposites.
The nanobiocomposites, designed for neurotransmitter detection, specifically
Norepinephrine, were thoroughly characterized and evaluated using a range of analytical
techniques. These included X-ray Diffraction (XRD), Scanning Electron Microscopy
(SEM), Fourier-Transform Infrared Spectroscopy (FTIR), Raman Spectroscopy,
Ultraviolet-Visible Spectroscopy (UV), Cyclic Voltammetry (CV), Electrochemical
Impedance Spectroscopy (EIS), and Differential Pulse Voltammetry (DPV). The analyses
provided valuable insights into the structural, morphological, and electrochemical
properties of the fabricated nanobiocomposite electrode. These findings demonstrate its
potential for accurately detecting Norepinephrine in biological samples with high
sensitivity and selectivity.
