Graph Theory is playing a key role in applied and pure Mathematics. The scope of Graph Theory is expanding day by day. ‘ In this thesis, we computed some topological indices, Co-indices and reverse degree- based indices such as ffirst‘ and ‘second Zagreb‘co-index, first and‘second multiple ‘Zagreb co-index‘forgotton‘topological co-index, atom bond‘connectivity co- index,‘geometric arithmetic co-index , Balaban index and general‘Randic index ‘for‘∝ = 1, −1, 1 2 , − 1 2 ‘for Calcium Hydroxide. My thesis comprising of five chapters. In the first chapter, we will define some basic definitions. In the 2nd chapter, we will find topological indices of Calcium Hydroxide structure. In the 3rd chapter, we will find topological Co-Indices of Calcium Hydroxide structure. In the 4th chapter, we will find reverse degree based topological indices of Calcium Hydroxide structure. In the 5th chapter, we will present the conclusion of our thesis.