Muhammad Tahir HussainCIIT/SP20-RMT-003/LHRDr. Sana JavedLHR TP 76222026-05-072021https://repository.cuilahore.edu.pk/123456789/3882Topological indices are frequently used in the analysis of different chemical or molecular compounds including drugs. This thesis mainly deals with the computation of degree-based topological indices of the drug Astrgaloside IV and Benzenoid and the construction of a network of the indices. The main objective is to detect the subnetworks of the network with highly connected links called modules and the master regulators in that module. This approach would help the researchers to investigate the physio-chemical characteristics of a Astrgaloside IV based on the master regulatory index in the module where a master regulator index is an index that is at the top of a regulatory hierarchy in a module and is not influenced by any other index. This thesis is divided into five chapters. Chapter 1 includes the basic definitions , notions , and terminologies related to this thesis. Chapter 2 provides a review of literature about our work. The main results are gives in chapter 3. Chapter 4 contains a bried discussion about the work while chapter 5 consists of the references used in this thesis.enDepartment of MathematicsSP20MathematicsAstragaloside IVconnectivity indiceschemical graph theoryDr. Sana JavedThesis