Muhammad Haroon YaqoobCIIT/FA20-RPH-016/LHRDr. Naima AminLHR TP 79792026-02-252022https://repository.cuilahore.edu.pk/handle/123456789/2259It has been long seen that patient given through ionizing radiation bring a chance of emerging a second cancer in their periods. Causes that contribute to the restate of cancer (or may be called second cancer) contains improved cancer being rate by using high radiations as well as developing treatment sense modality. They could enhance healthy tissues that were set aside from the goal volume for secondary experiences. In this paper, the Linear-Quadratic existence model for outside beam radiation therapy is examined through a focus on just how various radiation treatment development strategies can be impacted via various cancer repopulation kinetics. Tumor control probability (TCP) models are used to further analyze the LQ model. A high energy electron beam 6 MeV through linear accelerator is used to strike the target in cancer treatment. In general, radiotherapy has different energy of electron used for cancer treatment which depends on the various factors such as general patient health and history and the stage of the cancer. The major difficulty in the radiation in cancer treatment is that electron beam did not recognize the distinction between healthy and diseased cell. External beam radiotherapy is used to deliver the radiations to the organ. Pelvic organ selected as a target volume. The pelvic organs include surrounding tissues/ organ at risk (OARs) such as per bladder, rectum, small bowl, Left and Right femoral heads. Thus, the purpose of this learning is to analyze and calculate the consequence of high energy electrons on these surrounding tissues of pelvic. Thus Mathematical & biological model, Linear quadratic model (LQM) is used as a tool to calculate the Biological Effective Dose (BED) and Biological Equivalent Dose (EQD2) with dose per fraction 2 for different Organs at Risk (OAR’s) nearer to the pelvic. Moreover, the aim of this analysis is to require a kind of the principles and methods connected to scattered doses (electron beam) surrounding organ to check and optimize the dose plan in radiation therapy by brief a big compilation of dosimetry and medical surveys.enDepartment of PhysicsFA20PhysicsHigh Energy Electron BeamCancerous CellRadiation TherapyIREBRTLQMOARsBEDEQD2LT & RTPTVsDr. Naima AminThesis