Muhammad ShakeelSP22-RMT-006LHR TP 8714Dr. Mohsan Hassan2026-03-132023-03-13https://repository.cuilahore.edu.pk/handle/123456789/2796In this thesis, we have used the classical Pennes, Single-phase-lag (SPL) and Dual phase-lag (DPL) bio-heat transfer models to explore the temperature distribution at the tumor position in multi-layered skin tissues such as (tumor, fat, dermis, muscle and subcutaneous). We studied the impact of heat transmission, including external heat source, and metabolic heat source, in various layers of skin tissue under these three models and use the boundary conditions different tissue. The problem is solved by finite difference method for predicting and comparing the results of the models.enDepartment of MathematicsMathematicsSP22TissueMathematical ModelsThesis